Superior Antiaging

Michael P Notorangelo DO ABAM CMRO 

Testing:
In medicine with our current level of knowledge and technology, we now can identify, quantify and manipulate aging and the early risks factors for secondary diseases such as cancer, heart disease and diabetes.

At Superior Antiaging we use 3 tests: Multimodal, Glycation and Functional. 
These 3 tests provide highly advanced age testing at the cellular level with high Sensitivity and high Specificity. (In that it correctly identifies the presence and absence of diseases tested for)
We use highly advanced program software that detects, identifies & quantifies earliest signs of aging and disease at the cellular level.

Test 1: Multimodal
It is a 2-day process,

Day 1 -Tests are performed resulting in your age scores and report
 Day 2 –Review of testing with Dr No
 -Best to bring your significant other to review important dietary and behavioral changes and suggestions for supplements as indicated so that you both understand the game plan.

Overview:
Multimodal testing using 2000 data points, identifies & quantifies 20 biomarkers.

Results are color coded for each biomarker based on a continuum of severity from Green-Yellow-Orange-Red.

Good news- All biomarkers respond to proper changes made, the earlier the better!
Bad News - Without changes, all Yellows will progress to Oranges, all Oranges will progress to Reds.
Goal of testing – eliminate the 30 years of misery associated with the early onset of chronic disease.

The program software directs the clinician through the testing process including the use of equipment and what you need to do to complete the test, such as blow into a tube, breathe deeply and stand up as directed. The clinician will guide you through these maneuvers.

As the software and equipment are exquisitely sensitive, to get the most accurate readings, it is very important to closely follow the clinician’s lead.
 This will include trying to focus on remaining still, relaxed and only speaking when directed until the testing is completed.

Testing is noninvasive using 7 points of contact on your skin. You will be placed in a fully reclining chair, and asked to remove your shoes and socks, it’s important that you wear appropriate clothing so that Blood pressure cuffs can be easily placed on both upper arms and both ankles. It’s important that your skin has no lotion use for 3 days, no bronzing lotions for 1 week, and no caffeine is consumed the morning of the test due to the sensitivity of the scanning equipment. It’s recommended that you bathe either the night before or optimally the morning of testing so that your skin is clean and dry for good adhesion. Electrodes connected to sticky pads will be placed on the soles of your feet and a pulse oximeter will be placed on your index finger.

If you are ill, or have been ill in the last 7 days, please call to reschedule the testing as the inflammation from your illness will affect the test results. We are looking for inflammation on the cellular level and the testing will pick up on this and provide incorrect results. Again, the testing equipment, though simple in appearance, is extremely sensitive and for your results to be accurate it is imperative that you follow these instructions explicitly.

The 2 most important Biomarkers are Insulin Resistance and Endothelium.
Insulin resistance is a major driving force for accelerated aging, chronic disease progression and increased risk for heart attack and stroke.
Endothelium, the proverbial “canary in the coalmine”, is as delicate as it is critical to the production of Nitrous Oxide.

We will be checking your circulation from arteries (circulation) down to your capillaries (microcirculation) for any restrictions of blood flow which translate into accelerated aging. 
Inflammation is a major catalyst for accelerated aging and chronic disease compromising blood flow.

We will check your sweat gland and microcirculatory function on the soles of your feet which quantify neurologic function and Nitrous Oxide production. Nitrous Oxide, again, is one of the most important indicators of the wellness produced by your endothelium, and critical to maintaining optimal blood flow. Remember, any decrease in blood flow accelerates aging

Testing will evaluate the responsiveness of your heart to mild challenges, blowing into a tube, deep breathing, standing up, provide data points of reference. Your heart like other striated muscle has reflexes
 It will also test your heart rate variability. This is a function of your heart’s responsiveness to its ever-changing environment and feedback mechanisms with the brain. This is the balance between the Sympathetic and Parasympathetic nervous systems. Decreased reactivity is a sign of accelerated aging.

Testing will check for arterial stiffness, i.e., hardening of the arteries, indicative of accelerated aging.

Testing will look for signs of increased emotional stress, another sign of accelerated aging

All data is then combined into a score for your Cardiometabolic risk or CMR. It is a scale of wellness, incorporating all 20 biomarkers as a snapshot of overall metabolic function.

Superior Antiaging uses state of the art equipment patented, proprietary and founded on university-based studies measuring the current functioning of your heart, circulatory and nervous systems.
Markers used have been compared to the gold standards for the detection of diseases with high sensitivity and specificity, meaning that the testing is highly capable of substantiating the presence or absence of diseases.
Testing will provide the information that you need to know so that you can make the changes necessary to extend your health-span.

Michael P. Notorangelo DO ABAM CMRO

 Diplomate: National Board of Osteopathic Medical Examiners,

 American Osteopathic Board of Neurology and Psychiatry,

 American Board of Addiction Medicine,

Medical Review Officer Certification Council